Quantification of Isoprostanes as an Index of Oxidative Stress: A Update
نویسندگان
چکیده
منابع مشابه
Quantification of F2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method.
Free radical-induced lipid peroxidation has been implicated in a number of human diseases including atherosclerosis, cancer, and neurodegenerative diseases. F(2)-Isoprostanes (IsoPs) are isomers of prostaglandin PGF(2alpha) that are generated in vivo from the free radical-initiated peroxidation of arachidonic acid independent of cyclooxygenase enzymes. Since the discovery of the IsoPs in the ea...
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Oxidative stress, characterized by an imbalance between increased exposure to free radicals and antioxidant defenses, is a prominent feature of many acute and chronic diseases and even the normal aging process. However, definitive evidence for this association has often been lacking due to recognized shortcomings with methods previously available to assess oxidant stress status in vivo in human...
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Oxidative stress is believed to be one of the major factors behind several acute and chronic diseases, and may also be associated with ageing. Excess formation of free radicals in miscellaneous body environment may originate from endogenous response to cell injury, but also from exposure to a number of exogenous toxins. When the antioxidant defence system is overwhelmed, this leads to cell dama...
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Isoprostanes are a recently discovered group of prostaglandin isomers. Results of previous studies suggest that they can be used as oxidative stress markers, because in a number of cardiovascular, pulmonary and neurological diseases their levels in biological samples considerably increase. It has been found that people suffering from diabetes, obesity, homozygous familial hypercholesterolemia, ...
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Abstract Background: In this article "Student to Staff Index" was improved by implying student grades and staff academic ranks in every institute as a new "Standard S. to S. Index". Also "Utilized S. from S. Index" was introduced for controlling and ranking the private universities. Methods: This index uses the numbers of classes a...
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ژورنال
عنوان ژورنال: Journal of Biological Sciences
سال: 2006
ISSN: 1727-3048
DOI: 10.3923/jbs.2006.469.479